
The Medicines Monitoring Unit at the University of Dundee is running a new type of study that aims to improve the effectiveness and safety of commonly prescribed medicines. This is called the EVIDENCE study (EVaulating Diuretics in Normal Care). In this particular study we are comparing two very similar medications used in the treatment of hypertension (high blood pressure), BENDROFLUMETHAZIDE and INDAPAMIDE.
The study works by assigning GP practices to follow a prescribing policy regarding which diuretic they use in the treatment of hypertension. Currently either can be prescribed. Doctors in participating practices use the assigned policy to guide their prescribing choices and, where clinically appropriate, patients have their regular medications altered in-line with the policy. Routinely collected NHS data will be used to compare the safety and effectiveness of the medications so that, in future, doctors and patients have all the information they need to make the best treatment choices.
If you would like to know more about the more about the EVIDENCE study, please email evidence@dundee.ac.uk or call the EVIDENCE team on 01382 383865. If you would like to know more about other trials that we are running please visit us at: www.memoresearch.com
Please see the video below for a short overview of the EVIDENCE study.
Frequently Asked Questions
What is blood pressure?
Blood pressure is the pressure of blood in your arteries, which are the vessels that carry blood from your heart to your brain and the rest of your body. A certain amount of pressure is required to circulate blood throughout your body.
Your blood pressure naturally rises and falls throughout the day and night, and it is normal for it to rise while you are active. It’s when your overall blood pressure is consistently high, even when resting, that action needs to be taken.
What is high blood pressure (hypertension)?
Need to get in touch?
By Post
EVIDENCE Study,
MEMO Research, Level 7,
Ninewells Hospital and Medical School,
Dundee, UK,
DD2 1GZ
By Phone
01382 383865
Monday to Friday
8.45am to 5.00pm
Resources
For more detailed information about the study, please click the link below to open the Patient Information Sheet for this study. Please also feel free to visit the NHS "Changing Your Medication" and NICE guidelines links below. On those pages, you will find official NHS policy on changing existing prescriptions for taking part in studies, and the guidelines that we adhere to for this type of reasearch.




The team
Here to help you

Angela Flynn
Study pharmacist responsible for implementing the study in GP practices. She also provides training for other pharmacists throughout Scotland.

Dr Alex Doney
Senior Clinical Lecturer at the University of Dundee and Honorary Consultant Physician at Ninewells Hospital with a specialist interest in Blood Pressure and Cardiovascular risk.
